BAY-707 [2109805-96-9]

MedChem Express

BAY-707 [2109805-96-9]

5

2109805-96-9

Research Use Only

99.64

C15H20N4O2

288.34

BAY-707 is a substrate-competitive, highly potent and selective inhibitor of MTH1(NUDT1) with an IC50 of 2.3 nM. BAY-707 has a good pharmacokinetic (PK) profile to other MTH1 compounds and is well-tolerated in mice, but shows a clear lack of in vitro or in vivo anticancer efficacy[1].

O=C(NCC)C(N1)=CC2=C1N=CC=C2N3CCOC[C@@H]3C

-20°C,2°C to 8°C

12352200