BAY-866 [1836185-18-2]
HY-126180
CAS Number1836185-18-2
Product group Chemicals
Molecular Weight596.29
Overview
- SupplierMedChem Express
- Product NameBAY-866 [1836185-18-2]
- Delivery Days Customer999
- CAS Number1836185-18-2
- CertificationResearch Use Only
- Molecular FormulaC19H13F4IN4O4S
- Molecular Weight596.29
- Scientific DescriptionBAY-866, a sulfamide campound, is an allosteric MEK1 inhibitor with an IC50 of 14 nM. BAY-866 inhibits cell growth of A375 (BRAF) and HCT116 (K-Ras) with IC50s of 13 nM and 277 nM, respectively. BAY-866 inhibits tumor growth in K-Ras-mutated A549 xenograft model[1].
- SMILESO=C(C1=C(C=C(C(F)=C1NC2=CC=C(C=C2F)I)F)OC3=CC=C(C(NS(=O)(N)=O)=C3)F)N
- UNSPSC12352200