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BAY 87-2243

M4869
AbMole BioScience
CAS Number1227158-85-1
DownloadDatasheet
Product group Chemicals
Estimated Purity0.9886
Molecular Weight525.53
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    BAY 87-2243
  • Delivery Days Customer
    9
  • CAS Number
    1227158-85-1
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Estimated Purity
    0.9886
  • Molecular Formula
    C26H26F3N7O2
  • Molecular Weight
    525.53
  • Scientific Description
    BAY87-2243 is a potent inhibitor of selective hypoxia-inducible facin-1 (HIF-1). Bay87-2243 induces iron death and necrosis in BRAFV600E melanoma cells by inhibiting the mitochondrial respiratory chain, resulting in ROS accumulation, lipid peroxidation, and GSH deletion.
  • SMILES
    CC1=CC(=N[N]1CC2=CC=NC(=C2)N3CCN(CC3)C4CC4)C5=NC(=NO5)C6=CC=C(OC(F)(F)F)C=C6
  • UNSPSC
    12352200

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