BAY11-7082, E2 Ubiquitin Conjugating Enzyme Inhibitor

Bioss

BAY11-7082, E2 Ubiquitin Conjugating Enzyme Inhibitor

16

Research Use Only

98.0

BAY11-7082 is a potent and selective E2 ubiquitin (Ub) conjugating enzyme inhibitor. It inhibits the conjugation of Ub to a range of E2 enzymes and inhibits E2 enzyme mediated IkappaBalpha phosphorylation and indirectly decreases NF-kappab activity. BAY11-7082 also reversibly activates MAPK signaling and induces apoptosis of leukemic T cell and B-cell lymphoma cell lines.

-20°C

51202000