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Bazedoxifene (hydrochloride) [198480-56-7]

HY-A0031A
MedChem Express
CAS Number198480-56-7
Product group Chemicals
Molecular Weight507.06
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Bazedoxifene (hydrochloride) [198480-56-7]
  • Delivery Days Customer
    10
  • CAS Number
    198480-56-7
  • Certification
    Research Use Only
  • Molecular Formula
    C30H35ClN2O3
  • Molecular Weight
    507.06
  • Scientific Description
    Bazedoxifene hydrochloride (TSE-424 hydrochloride) is an oral active, BBB-penetrant nonsteroidal selective estrogen receptor modulator (SERM), with IC50s of 23 nM and 99 nM for ERalpha and ERbeta, respectively. Bazedoxifene hydrochloride can be used for the research of osteoporosis. Bazedoxifene hydrochloride acts as an inhibitor of IL-6/GP130 protein-protein interactions. Bazedoxifene hydrochloride can be used for the research of pancreatic cancer[1][2].
  • SMILES
    OC1=CC2=C(N(CC3=CC=C(OCCN4CCCCCC4)C=C3)C(C5=CC=C(O)C=C5)=C2C)C=C1.[H]Cl
  • UNSPSC
    12352200