BBO-10203

MedChem Express

BBO-10203

5

Research Use Only

99.12

C34H30F2N6O3S

640.70

BBO-10203 (Compound 758) binds to the RBD region of PI3Kalpha, and inhibits the binding of K-, H-, and N-Ras to PI3Kalpha. BBO-10203 inhibits pAKT with an IC50 [1].

CN(N=C1)C(C=C2)=C1C=C2C3=NC(C4=NN5C([C@@H](C)N(C(C=C)=O)CC5)=C4)=[C@]([C@]6=C(F)C=C(F)C=C6OCCOC)C7=C3C=CS7

-20°C,2°C to 8°C

12352200