BBR 2160 [118587-22-7]

TargetMol Chemicals

BBR 2160 [118587-22-7]

72

118587-22-7

Research Use Only

BBR 2160

C21H25N3O7S

463.5

BBR 2160 is a dihydropyridine derivative belonging to the group of the so-called tiampidine. BBR 2160 has calcium-antagonistic properties in cardiac tissue. Intracellular microelectrodes have been used to characterize the electrophysiological properties of BBR 2160 on guinea-pig papillary muscle and sheep Purkinje fibres. BBR 2160 (10(-7) and 10(-6) M) dose dependently decreased the contractility of driven papillary muscle and Purkinje fibre. This effect was associated with a lowering of the plateau phase and a shortening of action potential duration in papillary muscle.

3 years

C(OCC)(=O)C=1C(C(C(OC)=O)=C(C)NC1CSCCNC=O)C2=CC(N(=O)=O)=CC=C2

-20°C

12352200