BCH001

AbMole BioScience

BCH001

9

384859-58-9

Chemical

Research Use Only

C20H15F3N2O5

420.34

BCH001 is a quinoline derivative and a selective PAPD5 inhibitor. BCH001 restores telomerase activity and telomere length in pluripotent stem cells induced by congenital keratosis (DC). BCH001 did not inhibit poly (A) -specific ribonucase (PARN) or several other polynucleotide polymerases. PAPD5 is A nonnormalized Poly (A) polymerase with an unconventional RNA binding motif.

CCOC(=O)C1=CN=C2C=CC(=CC2=C1NC3=CC=CC=C3C(O)=O)OC(F)(F)F

12352200