Bcl-2 antibody [N1N2], N-term
GTX100064
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityCanine, Feline, Human, Mouse, Rat
TargetBCL2
Overview
- SupplierGeneTex
- Product NameBcl-2 antibody [N1N2], N-term
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.2 mg/ml
- ConjugateUnconjugated
- Gene ID596
- Target nameBCL2
- Target descriptionBCL2 apoptosis regulator
- Target synonymsBcl-2, PPP1R50, apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, protein phosphatase 1, regulatory subunit 50
- HostRabbit
- IsotypeIgG
- Protein IDP10415
- Protein NameApoptosis regulator Bcl-2
- Scientific DescriptionThis gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq]
- ReactivityCanine, Feline, Human, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Şen Ö, Emanet M, Mazzuferi M, et al. Microglia Polarization and Antiglioma Effects Fostered by Dual Cell Membrane-Coated Doxorubicin-Loaded Hexagonal Boron Nitride Nanoflakes. ACS Appl Mater Interfaces. 2023,15(50):58260-58273. doi: 10.1021/acsami.3c17097Read this paper
- Hua T, Chu Y, Wang M, et al. Protective effect of canagliflozin on post-resuscitation myocardial function in a rat model of cardiac arrest. Intensive Care Med Exp. 2023,11(1):78. doi: 10.1186/s40635-023-00562-yRead this paper
- Ballon Romero SS, Fuh LJ, Hung SY, et al. Electroacupuncture exerts prolonged analgesic and neuroprotective effects in a persistent dental pain model induced by multiple dental pulp injuries: GABAergic interneurons-astrocytes interaction. Front Immunol. 2023,14:1213710. doi: 10.3389/fimmu.2023.1213710Read this paper
- Liao CP, Hsieh YC, Lu CH, et al. Methoxyhispolon Methyl Ether, a Hispolon Analog, Thwarts the SRC/STAT3/BCL-2 Axis to Provoke Human Triple-Negative Breast Cancer Cell Apoptosis In Vitro. Biomedicines. 2023,11(10). doi: 10.3390/biomedicines11102742Read this paper
- Hasan AMR, Selim MA, Anne FI, et al. Opportunities and challenges in delivering maternal and child nutrition services through public primary health care facilities in urban Bangladesh: a qualitative inquiry. BMC Health Serv Res. 2023,23(1):1172. doi: 10.1186/s12913-023-10094-6Read this paper
- Zhou B, Wang L, Yang S, et al. Rosmarinic acid treatment protects against lethal H1N1 virus-mediated inflammation and lung injury by promoting activation of the h-PGDS-PGD(2)-HO-1 signal axis. Chin Med. 2023,18(1):139. doi: 10.1186/s13020-023-00847-0Read this paper
- Hsieh YC, Dai YC, Cheng KT, et al. Blockade of the SRC/STAT3/BCL-2 Signaling Axis Sustains the Cytotoxicity in Human Colorectal Cancer Cell Lines Induced by Dehydroxyhispolon Methyl Ether. Biomedicines. 2023,11(9). doi: 10.3390/biomedicines11092530Read this paper
- Al-Zahaby SA, Farag MR, Alagawany M, et al. Zinc Oxide Nanoparticles (ZnO-NPs) Induce Cytotoxicity in the Zebrafish Olfactory Organs via Activating Oxidative Stress and Apoptosis at the Ultrastructure and Genetic Levels. Animals (Basel). 2023,13(18). doi: 10.3390/ani13182867Read this paper
- Zhao Z, Yang Q, Zhou T, et al. Anticancer potential of Bacillus coagulans MZY531 on mouse H22 hepatocellular carcinoma cells via anti-proliferation and apoptosis induction. BMC Complement Med Ther. 2023,23(1):318. doi: 10.1186/s12906-023-04120-7Read this paper
- Jia L, Jingzhen Z, Xinliang Y, et al. 4-PBA inhibits endoplasmic reticulum stress to improve autophagic flux in the treatment of protamine/lipopolysaccharide-induced interstitial cystitis in rats. Sci Rep. 2023,13(1):14057. doi: 10.1038/s41598-023-38584-xRead this paper
Datasheet
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