
Analysis of Protein Array containing more than 19,000 full-length human proteins using bcl-6 Mouse Monoclonal Antibody (BCL6/1475). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SDs) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SDs) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target if the Monoclonal Antibody has an S-score of at least 2.5. For example, if a Monoclonal Antibody binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that Monoclonal Antibody to protein X is equal to 29.
BCL6 antibody [BCL6/1475]
GTX34432
ApplicationsWestern Blot, Other Application
Product group Antibodies
ReactivityHuman
TargetBCL6
Overview
- SupplierGeneTex
- Product NameBCL6 antibody [BCL6/1475]
- Delivery Days Customer9
- Application Supplier NoteWB: 1-2microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, Other Application
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDBCL6/1475
- Concentration0.2 mg/ml
- ConjugateUnconjugated
- Gene ID604
- Target nameBCL6
- Target descriptionBCL6 transcription repressor
- Target synonymsB cell CLL/lymphoma 6; B-cell lymphoma 5 protein; B-cell lymphoma 6 protein; B-cell lymphoma 6 protein transcript; BCL5; BCL-5; BCL-6; BCL6A; cys-his2 zinc finger transcription factor; LAZ3; lymphoma-associated zinc finger gene on chromosome 3; protein LAZ-3; ZBTB27; zinc finger and BTB domain-containing protein 27; zinc finger protein 51; zinc finger transcription factor BCL6S; ZNF51
- HostMouse
- IsotypeIgG1
- Protein IDP41182
- Protein NameB-cell lymphoma 6 protein
- Scientific DescriptionThe protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203