Bio-Connect

BCOR antibody [C-10]

Research Use Only
GTX01587
GeneTex
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetBCOR
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    BCOR antibody [C-10]
  • Delivery Days Customer
    9
  • Applications
    ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    C-10
  • Conjugate
    Unconjugated
  • Gene ID54880
  • Target name
    BCOR
  • Target description
    BCL6 corepressor
  • Target synonyms
    ANOP2; BCL-6 coreceptor; BCL-6 corepressor; BCL6 interacting corepressor; BCL-6 interacting corepressor; MAA2; MCOPS2
  • Host
    Mouse
  • Isotype
    IgG1
  • Scientific Description
    The protein encoded by this gene was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs. Several transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome Y.[provided by RefSeq, Jun 2010]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • BCOR Expression in Mullerian Adenosarcoma: A Potential Diagnostic Pitfall. Muthukumarana V et al., 2020 Jun, Am J Surg Pathol
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  • High-grade neuroepithelial tumor with BCOR exon 15 internal tandem duplication-a comprehensive clinical, radiographic, pathologic, and genomic analysis. Ferris SP et al., 2020 Jan, Brain Pathol
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  • Undifferentiated Uterine Sarcomas Represent Under-Recognized High-grade Endometrial Stromal Sarcomas. Cotzia P et al., 2019 May, Am J Surg Pathol
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