BCOR antibody [C-10]
GTX01587
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetBCOR
Overview
- SupplierGeneTex
- Product NameBCOR antibody [C-10]
- Delivery Days Customer9
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDC-10
- ConjugateUnconjugated
- Gene ID54880
- Target nameBCOR
- Target descriptionBCL6 corepressor
- Target synonymsANOP2; BCL-6 coreceptor; BCL-6 corepressor; BCL6 interacting corepressor; BCL-6 interacting corepressor; MAA2; MCOPS2
- HostMouse
- IsotypeIgG1
- Scientific DescriptionThe protein encoded by this gene was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs. Several transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome Y.[provided by RefSeq, Jun 2010]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- BCOR Expression in Mullerian Adenosarcoma: A Potential Diagnostic Pitfall. Muthukumarana V et al., 2020 Jun, Am J Surg PatholRead more
- High-grade neuroepithelial tumor with BCOR exon 15 internal tandem duplication-a comprehensive clinical, radiographic, pathologic, and genomic analysis. Ferris SP et al., 2020 Jan, Brain PatholRead more
- Undifferentiated Uterine Sarcomas Represent Under-Recognized High-grade Endometrial Stromal Sarcomas. Cotzia P et al., 2019 May, Am J Surg PatholRead more