BD-1008 (dihydrobromide) [138356-09-9]
HY-100966
CAS Number138356-09-9
Product group Chemicals
Estimated Purity98.07
Molecular Weight463.08
Overview
- SupplierMedChem Express
- Product NameBD-1008 (dihydrobromide) [138356-09-9]
- Delivery Days Customer14
- CAS Number138356-09-9
- CertificationResearch Use Only
- Estimated Purity98.07
- Molecular FormulaC15H24Br2Cl2N2
- Molecular Weight463.08
- Scientific DescriptionBD-1008 dihydrobromide is a nonselective sigma receptor antagonist with Kis against sigma1 receptor and sigma2 receptor of 2 nM and 8 nM. The BD-1008 dihydrobromide has an extremely low affinity for the D2 receptor (Ki = 1112 nM) and dopamine transporter (DAT) (Ki > 10,000 nM). BD-1008 dihydrobromide significantly antagonizes dopamine release in the shell region of the nucleus accumbens via the sigma2 receptor. BD-1008 dihydrobromide blocks the self-administration behavior of sigma agonists.BD-1008 dihydrobromide can be used for the study of addiction therapy that target the sigma receptor[1][2][3].
- SMILESCN(CCC1=CC=C(Cl)C(Cl)=C1)CCN2CCCC2.Br.Br
- Storage Instruction-20°C
- UNSPSC12352200
MSDS
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