Belnacasan (Standard) [273404-37-8]

MedChem Express

Belnacasan (Standard) [273404-37-8]

999

Research Use Only

Belnacasan (Standard) is the analytical standard of Belnacasan. This product is intended for research and analytical applications. Belnacasan (VX-765) is an orally bioactive proagent of VRT-043198, which is a potent and selective inhibitor of IL-converting enzyme (ICE)/caspase-1 with Kis of 0.8 nM and less than 0.6 nM for caspase-1 and caspase-4, respectively. Belnacasan (VX-765) inhibits the release of LPS-induced IL-1beta and IL-18 by human PBMCs with an IC50 of ~0.7 microM[1][2].

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