Belzutifan

MedChem Express

Belzutifan [1672668-24-4]

10

1672668-24-4

Research Use Only

99.85

C17H12F3NO4S

383.34

Belzutifan (PT2977) is an orally active and selective HIF-2alpha inhibitor with an IC 50 of 9 nM. Belzutifan, as a second-generation HIF-2alpha inhibitor, increases potency and improves pharmacokinetic profile. Belzutifan is a potential treatment for clear cell renal cell carcinoma (ccRCC) [1] .

N#CC1=CC(F)=CC(OC2=CC=C(S(=O)(C)=O)C3=C2[C@@H](F)[C@@H](F)[C@H]3O)=C1

-20°C

12352200