Bemcentinib
HY-15150
CAS Number1037624-75-1
Product group Chemicals
Estimated Purity99.92
Molecular Weight506.64
Overview
- SupplierMedChem Express
- Product NameBemcentinib [1037624-75-1]
- Delivery Days Customer10
- CAS Number1037624-75-1
- CertificationResearch Use Only
- Estimated Purity99.92
- Molecular FormulaC30H34N8
- Molecular Weight506.64
- Scientific DescriptionBemcentinib (R428) is a selective and orally active Axl inhibitor with an IC50 of 14 nM. Bemcentinib retards cancer cell migration and invasion. Bemcentinib exhibits >100-fold selectivity for Axl versus Abl and 50- and >100-fold selectivity over TAM family kinases Mer and Tyro3, respectively, in cells. Bemcentinib blocks tumor spread and prolongs survival in models of metastatic breast cancer[1][2].
- SMILESNC1=NC(NC2=CC(CC[C@@H](N3CCCC3)CC4)=C4C=C2)=NN1C(N=N5)=CC6=C5C7=CC=CC=C7CCC6
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
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CAS Number1037624-75-1
Estimated Purity99.73%
Molecular Weight506.64
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R428SYN-1131
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Estimated Purity>95%
Molecular Weight506.6
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Product group Chemicals
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CAS Number1037624-75-1
Estimated Purity98.57%
Molecular Weight506.64
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