Benzamil (hydrochloride)

MedChem Express

Benzamil (hydrochloride) [161804-20-2]

10

161804-20-2

Research Use Only

99.80

C13H15Cl2N7O

356.21

Benzamil hydrochloride (Benzylamiloride hydrochloride), an Amiloride analogue, is a Na + /Ca 2+ exchanger (NCX) inhibitor ( IC 50 ~100 nM). Benzamil hydrochloride also is a non-selective Deg/epithelial sodium channels (ENaC) blocker, and can potentiate myogenic vasoconstriction. Benzamil hydrochloride inhibits TRPP3-mediated Ca 2+ -activated currents, with an IC 50 of 1.1 microM [1] [2] [3] .

O=C(C1=NC(Cl)=C(N)N=C1N)NC(NCC2=CC=CC=C2)=N.[H]Cl

2°C to 8°C

12352200