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Benzamil (hydrochloride)

HY-B1546A
MedChem Express
CAS Number161804-20-2
DownloadMSDS
Product group Chemicals
Estimated Purity99.80
Molecular Weight356.21
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Benzamil (hydrochloride) [161804-20-2]
  • Delivery Days Customer
    10
  • CAS Number
    161804-20-2
  • Certification
    Research Use Only
  • Estimated Purity
    99.80
  • Molecular Formula
    C13H15Cl2N7O
  • Molecular Weight
    356.21
  • Scientific Description
    Benzamil hydrochloride (Benzylamiloride hydrochloride), an Amiloride analogue, is a Na + /Ca 2+ exchanger (NCX) inhibitor ( IC 50 ~100 nM). Benzamil hydrochloride also is a non-selective Deg/epithelial sodium channels (ENaC) blocker, and can potentiate myogenic vasoconstriction. Benzamil hydrochloride inhibits TRPP3-mediated Ca 2+ -activated currents, with an IC 50 of 1.1 microM [1] [2] [3] .
  • SMILES
    O=C(C1=NC(Cl)=C(N)N=C1N)NC(NCC2=CC=CC=C2)=N.[H]Cl
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200

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