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Benzo[c][1,8]naphthyridin-6(5H)-one [53439-81-9]

HY-115862
MedChem Express
CAS Number53439-81-9
Product group Chemicals
Molecular Weight196.20
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Benzo[c][1,8]naphthyridin-6(5H)-one [53439-81-9]
  • Delivery Days Customer
    5
  • CAS Number
    53439-81-9
  • Certification
    Research Use Only
  • Molecular Formula
    C12H8N2O
  • Molecular Weight
    196.20
  • Scientific Description
    Benzo[c][1,8]naphthyridin-6(5H)-one exhibits low micromolar affinity to human adenosine receptor (AR) A1 and hA2A, with Ki of 4.6 and 4.8 microM. Benzo[c][1,8]naphthyridin-6(5H)-one is inhibitor for poly ADP-ribose polymerase-1 (PARP-1) and aurora kinase A, with IC50 of 0.311 and 5.5 microM[1][2][3].
  • SMILES
    O=C1NC2=NC=CC=C2C3=CC=CC=C13
  • UNSPSC
    12352200