Benzoylaconine [466-24-0]

MedChem Express

Benzoylaconine [466-24-0]

10

466-24-0

Research Use Only

99.92

C32H45NO10

603.70

Benzoylaconine (Benzoylaconitine) is an orally active monoester alkaloid found in the traditional Chinese medicine Aconitum carmichaelii. Benzoylaconine is an ACE2 agonist (EC50: 1.5 microM) with antihypertensive and anti-heart failure effects. Benzoylaconine inhibits TLR-induced MAPK and NF-kappaB pathways to exert anti-inflammatory effects. Benzoylaconine upregulates the protein levels of P-gp, MRP2, and has anti-tumor effects[1][2][3][4][5][6].

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2°C to 8°C

12352200