Besifovir Dipivoxil [441785-26-8]

MedChem Express

Besifovir Dipivoxil [441785-26-8]

9

441785-26-8

Research Use Only

C22H34N5O8P

527.51

Besifovir Dipivoxil (LB-80380), an analog of guanosine monophosphate, is an acyclic nucleotide phosphonate with antiviral effect. Besifovir Dipivoxil is rapidly converted by the liver and intestine to the intermediate metabolite LB80331 via the esterification process, subsequently phosphorylated into the di- and triphosphate forms, which act as antiviral DNA synthesis inhibitors. Besifovir Dipivoxil is promising for research of chronic hepatitis B[1].

CC(C)(C)C(OCOP(COC1(CC1)CN2C3=NC(N)=NC=C3N=C2)(OCOC(C(C)(C)C)=O)=O)=O

12352200