BET-IN-20
HY-149735
Overview
- SupplierMedChem Express
- Product NameBET-IN-20 [1300735-76-5]
- Delivery Days Customer14
- CertificationResearch Use Only
- Molecular FormulaC25H24N4O2
- Molecular Weight412.48
- Scientific DescriptionBET-IN-20 (compound 10) is an inhibitor of BRD4 BD1 (IC50=1.9 nM) with anticancer activity. BET-IN-20 can promote acute myeloid leukemia (AML) cell apoptosis and arrest the cell cycle in the G0/G1 phase. BET-IN-20 also inhibits c-Myc and CDK6 and enhances PARP cleavage[1].
- SMILESC[C@H](C1=CC=CC=C1)N2C(C3=C4)=C(N=C2C)C=NC3=CC(C5=C(C)ON=C5C)=C4OC
- UNSPSC12131703