beta-Apooxytetracycline [18751-99-0]

TargetMol Chemicals

beta-Apooxytetracycline [18751-99-0]

44

18751-99-0

Chemical

Research Use Only

bèta-Apooxytetracycline

C22H22N2O8

442.424

beta-Apooxytetracycline is a potential impurity found in commercial preparations of oxytetracycline. beta-Apooxytetracycline is a degradation product formed from oxytetracycline via acid hydrolysis. It has a relative potency of 0.1 compared with oxytetracycline for inhibiting the growth of aerobic sludge bacteria, an MIC50 value of 32 mg/L for tetracycline-sensitive strains of Pseudomonas, and MIC50 values of greater than 32 mg/L for tetracycline-sensitive strains of Agrobacterium, Moraxella, and Bacillus, as well as tetracycline-resistant strains of E. coli. beta-Apooxytetracycline (10 mg/kg) is toxic to rats, decreasing body weight, disrupting blood cell counts, and inducing hepatocyte necrosis.

3 years

[H][C@@]1(OC(=O)c2c1c(C)c1cccc(O)c1c2O)[C@@]1([H])[C@@H](O)C(=O)C(C(N)=O)=C(O)[C@H]1N(C)C

-20°C

51280000