beta-Naphthoflavone-CH2-OH
HY-130269
Product group Molecular Biology
Overview
- SupplierMedChem Express
- Product Namebeta-Naphthoflavone-CH2-OH
- Delivery Days Customer10
- CertificationResearch Use Only
- Molecular FormulaC20H14O3
- Molecular Weight302.32
- Scientific Descriptionbeta-Naphthoflavone-CH2-OH (beta-NF-CH2-OH) is a ligand for arylhydrocarbon receptor (AhR) E3 ligase. beta-Naphthoflavone-CH2-OH can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs (e.g., beta-naphthoflavone-JQ1) that recruit the AhR E3 ligase complex by incorporating AhR ligands into chimeric molecules. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins [1].
- SMILESO=C1C=C(C2=CC=C(CO)C=C2)OC3=C1C4=CC=CC=C4C=C3
- UNSPSC41115800