beta-Spaglumic acid [4910-46-7]

MedChem Express

beta-Spaglumic acid [4910-46-7]

10

4910-46-7

Research Use Only

C11H16N2O8

304.25

beta-Spaglumic acid (beta-NAAG) is a competitive NAAG peptidase inhibitor (Ki=1 microM) that protects spinal cord neurons from excitotoxicity and hypoxic damage. beta-Spaglumic acid is also a selective mGluR3 antagonist (mGluR3 receptor functions to regulate activity-dependent synaptic potentiation in the hippocampus). beta-Spaglumic acid can be used in neuroprotection-related studies[1][2].

O=C(O)CC[C@@H](C(O)=O)NC(C[C@@H](C(O)=O)NC(C)=O)=O

12352200