beta,beta-Dimethylacrylshikonin

MedChem Express

beta,beta-Dimethylacrylshikonin [24502-79-2]

10

24502-79-2

Research Use Only

99.30

C21H22O6

370.40

beta,beta-Dimethylacrylshikonin (Isoarnebin I) is a naphthoquinone derivative that can be isolated from Lithospermum erythrorhizon Sieb. et Zucc. beta,beta-Dimethylacrylshikonin promotes angiogenesis by inducing eNOS, VEGF and HIF-1alpha expression through the PI3K-dependent pathway. beta,beta-Dimethylacrylshikonin inhibits Notch-1 activation. beta,beta-Dimethylacrylshikonin inhibtis tumor cell proliferation, induces tumor cell apoptosis, and inhibits tumor growth[1][2][3][4].

O=C1C2=C(O)C=CC(O)=C2C(C=C1[C@@H](C/C=C(C)/C)OC(/C=C(C)/C)=O)=O

2°C to 8°C

12352200