IHC-P analysis of mouse kidney tissue using GTX85010 BFAR antibody. Working concentration : 5 microg/ml
IHC-P analysis of mouse kidney tissue using GTX85010 BFAR antibody. Working concentration : 5 microg/ml
BFAR antibody
GTX85010
Overview
- SupplierGeneTex
- Product NameBFAR antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1 - 2 microg/mL. IHC-P: 5 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- Concentration1 mg/ml
- FormulationLiquid
- Gene ID51283
- Target nameBFAR
- Target descriptionbifunctional apoptosis regulator
- Target synonymsBAR; bifunctional apoptosis inhibitor; bifunctional apoptosis regulator; RING finger protein 47; RNF47
- Protein IDQ9NZS9
- Protein NameBifunctional apoptosis regulator
- Scientific DescriptionThe bifunctional apoptosis inhibitor (BFAR) is scaffold protein that integrates signaling components of the cells apoptosis-regulatory machinery. BFAR is a multidomain protein capable of inhibiting apoptosis induced by TNF-family death receptors (extrinsic pathway) as well as mitochondria-dependent apoptosis (intrinsic pathway). Interaction of BFAR with Bcl-2 or Bcl-XL via a SAM domain may contribute to the anti-apoptotic properties of BFAR. In addition, BFAR contains a DED-like domain that is capable of suppressing apoptosis mediated at the receptor level. BFAR is also thought to be involved in the regulation of neuronal survival.
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203