BFMO

MedChem Express

BFMO [69010-90-8]

5

69010-90-8

Research Use Only

99.84

C12H12N2O4

248.238

BFMO is a bidentate ligand for copper (Cu) catalysts that can effectively promote copper-catalyzed N-arylation coupling reactions of (hetero)aryl bromides with aniline, cyclic secondary amines, and acyclic secondary amines. BFMO coordinates with copper ions to form stable catalytically active species, which reduces the activation energy of the reaction and improves the reactivity of the substrate. It exhibits excellent selectivity for coupling of acyclic secondary amines with large steric hindrance, and can achieve direct monoarylation of piperazine with (hetero)aryl bromides to generate important pharmaceutical structural units[1][2].

O=C(C(NCC1=CC=CO1)=O)NCC2=CC=CO2

-20°C,2°C to 8°C

12352200