BGB-8035 [2283349-24-4]

MedChem Express

BGB-8035 [2283349-24-4]

10

2283349-24-4

Research Use Only

99.00

C24H31N5O4

453.53

BGB-8035 is an orally active, highly selective brutons tyrosine kinase (BTK) inhibitor with IC50s of 1.1 nM, 99 nM, 621 nM for BTK, TEC, EGFR, respectively. BGB-8035 has antitumor and anti-arthritis activity. BGB-8035 has the potential for B-cell malignancies and autoimmune diseases research[1].

C=CC(N1CCC(CC1)[C@@H]2CCNC3=C(C(C4=CC(OC)=C(C(OC)=C4)C)=NN32)C(N)=O)=O

-20°C

12131703