BH3I-2 [315195-18-7]

TargetMol Chemicals

BH3I-2 [315195-18-7]

72

315195-18-7

Chemical

Research Use Only

BH3I-2'

C19H11Cl3INO4S

582.62

BH3I-2 is a cell-permeable BH3 mimetic. BH3I-2 induces apoptosis by specifically preventing BH3 domain-mediated interactions between pro-apoptotic and anti-apoptotic members of the Bcl-2 family, thereby blocking the interaction between Bcl-x and Bak BH3 by targeting the Bcl-x binding pocket.

3 years

S(=O)(=O)(C1=CC(NC(=O)C2=C(O)C(I)=CC(Cl)=C2)=C(Cl)C=C1)C3=CC=C(Cl)C=C3

-20°C

12352200