BHA536

MedChem Express

BHA536

9

Research Use Only

C30H30ClN3O5

548.03

BHA536 is an orally active selective inhibitor for PKCalpha/beta and NF-kB signaling pathway. BHA536 inhibits the proliferation of CD79-mutated ABC DLBCL cell, arrests cell cycle at G1 phase, and induces apoptosis in TMD8 cell. BHA536 exhibits antitumor efficacy in mice[1].

CN(C)CC1=CC2=C(C=C1)C=CC(Cl)=C2C3=C(C4=CNC5=C4C=CC=C5OCCOCCOC)C(NC3=O)=O

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