BI-2865

AbMole BioScience

BI-2865

9

2937327-93-8

Chemical

Research Use Only

C23H27N7O2S

465.57

BI-2865 is a non-covalent pan-KRAS inhibitor that binds to KRAS WT, G12C, G12D, G12V, and G13D mutants with Kd values of 6.9 nM, 4.5 nM, 32 nM, 26 nM, and 4.3 nM, respectively.It can be used in studies related to KRAS mutant tumors.

CC(OC1=NC(=NC=C1)C2=NOC(=N2)C3(C)CCCC4=C3C(=C(N)S4)C#N)C5CCCN5C

12352200