BI 653048 [1198784-72-3]
HY-12946
CAS Number1198784-72-3
Product group Chemicals
Estimated Purity99.84
Molecular Weight515.52
Overview
- SupplierMedChem Express
- Product NameBI 653048 [1198784-72-3]
- Delivery Days Customer10
- CAS Number1198784-72-3
- CertificationResearch Use Only
- Estimated Purity99.84
- Molecular FormulaC23H25F4N3O4S
- Molecular Weight515.52
- Scientific DescriptionBI 653048 is a selective and orally active nonsteroidal glucocorticoid (GC) agonist with an IC50 value of 55 nM[1]. BI 653048 inhibits CP1A2, CYP2D6, CYP2C9, CYP2C19 and CYP3A4 isoforms activity and reduces affinity for the hERG ion channel (IC50>30 microM)[2]. BI 653048 (Compound 103) is also a HCV NS3 protease inhibitor that can reduce viral loads infected with the hepatitis C virus[3].
- SMILESO=C(N)C1=CC(F)=CC=C1C(C)(C)C[C@@](O)(CC(N2)=CC3=C2C=NC(S(=O)(CC)=O)=C3)C(F)(F)F
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
![BI 653048 [1198784-72-3]](https://www.targetmol.com/group3/M00/02/3B/CgoaEGY7LSmEPa9hAAAAAAJQASQ600.png)