Bio-Connect

BI 653048 [1198784-72-3]

HY-12946
MedChem Express
CAS Number1198784-72-3
Product group Chemicals
Estimated Purity99.84
Molecular Weight515.52
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Overview

  • Supplier
    MedChem Express
  • Product Name
    BI 653048 [1198784-72-3]
  • Delivery Days Customer
    10
  • CAS Number
    1198784-72-3
  • Certification
    Research Use Only
  • Estimated Purity
    99.84
  • Molecular Formula
    C23H25F4N3O4S
  • Molecular Weight
    515.52
  • Scientific Description
    BI 653048 is a selective and orally active nonsteroidal glucocorticoid (GC) agonist with an IC50 value of 55 nM[1]. BI 653048 inhibits CP1A2, CYP2D6, CYP2C9, CYP2C19 and CYP3A4 isoforms activity and reduces affinity for the hERG ion channel (IC50>30 microM)[2]. BI 653048 (Compound 103) is also a HCV NS3 protease inhibitor that can reduce viral loads infected with the hepatitis C virus[3].
  • SMILES
    O=C(N)C1=CC(F)=CC=C1C(C)(C)C[C@@](O)(CC(N2)=CC3=C2C=NC(S(=O)(CC)=O)=C3)C(F)(F)F
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200