Bicuculline [485-49-4]
HY-N0219
CAS Number485-49-4
Product group Chemicals
Estimated Purity99.97
Molecular Weight367.35
Overview
- SupplierMedChem Express
- Product NameBicuculline [485-49-4]
- Delivery Days Customer10
- CAS Number485-49-4
- CertificationResearch Use Only
- Estimated Purity99.97
- Molecular FormulaC20H17NO6
- Molecular Weight367.35
- Scientific DescriptionBicuculline ((+)-Bicuculline) is A competing neurotransmitter GABAA receptor antagonist (IC50=2 microM). Bicuculline also blocks Ca2+ activating potassium (SK) channels and subsequently blocks slow post-hyperpolarization (slow AHP). Bicuculline has anticonvulsant activity. Bicuculline can be used to induce seizures in mice[1][2][3][4].
- SMILESO=C1O[C@@H]([C@H]2N(C)CCC3=C2C=C(OCO4)C4=C3)C5=CC=C(OCO6)C6=C51
- Storage Instruction2°C to 8°C
- UNSPSC12352200
MSDS
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