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Bicuculline

HY-N0219
MedChem Express
CAS Number485-49-4
Product group Chemicals
Estimated Purity99.97
Molecular Weight367.35
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Bicuculline [485-49-4]
  • Delivery Days Customer
    10
  • CAS Number
    485-49-4
  • Certification
    Research Use Only
  • Estimated Purity
    99.97
  • Molecular Formula
    C20H17NO6
  • Molecular Weight
    367.35
  • Scientific Description
    Bicuculline ((+)-Bicuculline) is A competing neurotransmitter GABAA receptor antagonist (IC50=2 microM). Bicuculline also blocks Ca2+ activating potassium (SK) channels and subsequently blocks slow post-hyperpolarization (slow AHP). Bicuculline has anticonvulsant activity. Bicuculline can be used to induce seizures in mice[1][2][3][4].
  • SMILES
    O=C1O[C@@H]([C@H]2N(C)CCC3=C2C=C(OCO4)C4=C3)C5=CC=C(OCO6)C6=C51
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200

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