Bicuculline (methochloride) [38641-83-7]

MedChem Express

Bicuculline (methochloride) [38641-83-7]

5

38641-83-7

Research Use Only

99.35

C21H20ClNO6

417.84

Bicuculline ((+)-Bicuculline; d-Bicuculline) methochloride is a selective GABAA receptor antagonist with an IC50 value of 3 microM. Bicuculline methochloride induces clonic tonic convulsions in mammals and can also be used to block Ca2+ activated potassium channels. Bicuculline methochloride can be used in studies of epilepsy and other related psychiatric disorders[1][2].

C[N+]([C@](C1=C2C=C3C(OCO3)=C1)([H])[C@@](O4)([H])C(C=CC5=C6OCO5)=C6C4=O)(CC2)C.[Cl-]

2°C to 8°C

12131703