WB analysis of (A) 5 and (B) 25 ng Bim recombinant protein using GTX84981 Bim antibody [1C2C8]. Working concentration : 1 microg/ml
Bim antibody [1C2C8]
GTX84981
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetBCL2L11
Overview
- SupplierGeneTex
- Product NameBim antibody [1C2C8]
- Delivery Days Customer9
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID1C2C8
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID10018
- Target nameBCL2L11
- Target descriptionBCL2 like 11
- Target synonymsBAM; bcl-2 interacting mediator of cell death; bcl-2 interacting protein Bim; BCL2-like 11 (apoptosis facilitator); bcl-2-like protein 11; bcl-2-related ovarian death agonist; BIM; BOD
- HostMouse
- IsotypeIgG1
- Scientific DescriptionMembers in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. Bim is another BH3 domain containing protein which can induce apoptosis. Bim interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. The messenger RNA of Bim is ubiquitously expressed in multiple tissues and cell lines.
- ReactivityHuman, Mouse
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203