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Bim blocking peptide

Research Use Only
GTX31697-PEP
GeneTex
ApplicationsNeutralisation/Blocking
Product group Proteins / Signaling Molecules
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    Bim blocking peptide
  • Delivery Days Customer
    9
  • Applications
    Neutralisation/Blocking
  • Certification
    Research Use Only
  • Concentration
    200 ug/ml
  • Conjugate
    Unconjugated
  • Scientific Description
    The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Jul 2008]
  • Storage Instruction
    -20°C
  • UNSPSC
    12352202