BIO
M7627
CAS Number667463-62-9
Product group Chemicals
Molecular Weight356.17
Overview
- SupplierAbMole BioScience
- Product NameBIO
- Delivery Days Customer9
- CAS Number667463-62-9
- Category SupplierChemical
- CertificationResearch Use Only
- Molecular FormulaC16H10BrN3O2
- Molecular Weight356.17
- Scientific DescriptionBIO (GSK-3 Inhibitor IX, 6-bromoindirubin-3-oxime, 6-Bromoindirubin-3'-oxime, MLS 2052) is a specific GSK-3 inhibitor, the IC50 acting on GSK-3alfa/bèta in cell-free assays is 5 nM, which is more than 16 times more selective than ACTing on CDK5. It is also a pan-JAK inhibitor with an IC50 value of 30 nM for Tyk2. BIO induces apoptosis in human melanoma cells.
- SMILESO\N=C/1\C(NC2=CC=CC=C12)=C3\C(=O)NC4=C3C=CC(=C4)Br
- UNSPSC12352200
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