Biotin Anti-Mouse CD132 Antibody

RD20288F
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityMouse
TargetIl2rg
Overview
- SupplierReddot Biotech
- Product NameBiotin Anti-Mouse CD132 Antibody
- Delivery Days Customer5
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Concentration0.5 mg/ml
- ConjugateBiotin
- Gene ID16186
- Target nameIl2rg
- Target descriptioninterleukin 2 receptor, gamma chain
- Target synonyms[g]c; CD132; common gamma chain; cytokine receptor common subunit gamma; gamm; gamma C receptor; gamma(; gamma(c); gc; IL-2 receptor subunit gamma; IL-2R subunit gamma; interleukin-2 receptor subunit gamma; p64
- HostRat
- IsotypeIgG2b
- Scientific DescriptionCD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, and is also known as common Oe≥ chain (Oe≥c) or IL-2 receptor Oe≥ subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID).
- ReactivityMouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203