Biotin-PEG1-azide [1204085-48-2]

MedChem Express

Biotin-PEG1-azide [1204085-48-2]

5

1204085-48-2

Research Use Only

99.88

C14H24N6O3S

356.44

Biotin-PEG1-azide is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Biotin-PEG1-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

O=C(CCCC[C@@H]1SC[C@@](N2)([H])[C@]1([H])NC2=O)NCCOCCN=[N+]=[N-]

-20°C

41115800