Biotinylated Human SIRP alpha V5 Protein (SRP-HM4V5B)

KACTUS

Biotinylated Human SIRP alpha V5 Protein (SRP-HM4V5B)

9

Research Use Only

Biotin

>95%

Tyrosine-protein phosphatase non-receptor type substrate 1

Signal regulatory protein alpha (SIRPalpha) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPalpha acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the dont eat me signal.Cancer cells highly expressed CD47 that activate SIRP alpha and inhibit macrophage-mediated destruction.

-20°C or -80°C,-80°C

12352202