BIRT 377

MedChem Express

BIRT 377 [213211-10-0]

10

213211-10-0

Research Use Only

99.82

C18H15BrCl2N2O2

442.13

BIRT 377 is a potent amd orally bioavailable inhibitor of the interaction between intercellular adhesion molecule-1 (ICAM-1) and lymphocyte function-associated antigen-1 (LFA-1) , with a K i of 25.8 nM. BIRT 377 also inhibits the production of IL-2 in vivo . BIRT 377 can be used for researching inflammatory and immune disorders [1] .

O=C1N(C2=CC(Cl)=CC(Cl)=C2)C(N(C)[C@]1(C)CC3=CC=C(Br)C=C3)=O

-20°C,2°C to 8°C

12352200