Bisacodyl

MedChem Express

Bisacodyl [603-50-9]

10

603-50-9

Research Use Only

99.71

C22H19NO4

361.39

Bisacodyl is a stimulant laxative agent that works directly on the colon to produce a bowel movement. Bisacodyl increases the secretion of PGE2 by direct activation of colon macrophages. PGE2 acts as a paracrine factor and decreases the expression of AQP3 in the colon, which inhibits water transfer from the luminal to the vascular side and leads to a laxative effect[1].

CC(OC1=CC=C(C(C2=CC=C(OC(C)=O)C=C2)C3=NC=CC=C3)C=C1)=O

-20°C,2°C to 8°C

12352200