Bisindolylmaleimide X (hydrochloride) [145317-11-9]
HY-108136A
CAS Number145317-11-9
Product group Chemicals
Estimated Purity98.90
Molecular Weight460.96
Overview
- SupplierMedChem Express
- Product NameBisindolylmaleimide X (hydrochloride) [145317-11-9]
- Delivery Days Customer10
- CAS Number145317-11-9
- CertificationResearch Use Only
- Estimated Purity98.90
- Hazard Informationh302, h315, h319, h335
- Molecular FormulaC26H25ClN4O2
- Molecular Weight460.96
- Scientific DescriptionBisindolylmaleimide X hydrochloride(Ro 31-8425 hydrochloride, BIM-X hydrochloride) is a cell-penetrating PKC inhibitor. Bisindolylmaleimide X hydrochloride is a potent cyclin-dependent kinase 2 (CDK2) antagonist with an IC50 of 200 nM. Bisindolylmaleimide X hydrochloride inhibits the proliferation of CD4 T cells in vitro. Bisindolylmaleimide X hydrochloride inhibits eNOS-Ser1177 phosphorylation in human embryonic vein endothelial cells. Bisindolylmaleimide X hydrochloride can be used for research on the immune system and cardiovascular diseases[1][2][3].
- SMILESO=C(C(C1=C(CC(CN)CC2)N2C3=C1C=CC=C3)=C4C5=CN(C)C6=C5C=CC=C6)NC4=O.[H]Cl
- Storage Instruction2°C to 8°C
- UNSPSC12352200
MSDS
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![Bisindolylmaleimide X hydrochloride [145317-11-9]](https://www.targetmol.com/group3/M00/35/45/CgoaEGayGmeEYXKTAAAAAMCgNV8464.png)
Product group Chemicals
References
CAS Number145317-11-9
Estimated Purity≥98%
Molecular Weight460.96
- SizePrice