Bisindolylmaleimide XI (hydrochloride)

MedChem Express

Bisindolylmaleimide XI (hydrochloride) [145333-02-4]

10

145333-02-4

Research Use Only

98.0

C28H29ClN4O2

489.01

Bisindolylmaleimide XI hydrochloride (Ro 32-0432) is a potent, selective and orally active PKC inhibitor with IC50s of 9 nM, 28 nM, 31 nM, 37 nM, and 108 nM for PKCalpha, PKCbetaI, PKCbetaII, PKCgamma, and PKCepsilon, respectively[1][2].

O=C(NC1=O)C(C2=C3CC(CCN3C4=C2C=CC=C4)CN(C)C)=C1C5=CN(C6=C5C=CC=C6)C.Cl

-20°C

12352200