Bis(maltolato)oxovanadium(IV)

MedChem Express

Bis(maltolato)oxovanadium(IV) [38213-69-3]

10

38213-69-3

Research Use Only

99.34

C12H10O7V

317.15

Bis(maltolato)oxovanadium(IV) (BMOV) is a potent, reversible, competitive and orally active pan- PTP (protein tyrosine phosphatases) inhibitor. Bis(maltolato)oxovanadium(IV) inhibits HCPTPA , PTP1B , HPTPbeta and SHP2 with IC 50 s of 126 nM, 109 nM, 26 nM and 201 nM, respectively. Bis(maltolato)oxovanadium(IV) is a potent insulin sensitizer [1] [2] .

O=[V+2]([O-]C1=C2C)([O]=C1C=CO2)([O]=C3C=CO4)[O-]C3=C4C

-20°C,2°C to 8°C

12352200