Bitopertin

AbMole BioScience

Bitopertin

9

845614-11-1

Research Use Only

C21H20F7N3O4S

543.46

Bitopertin (RG1678,RO-4917838) is a potent inhibitor of glycine transporter 1 (GlyT1), with Ki of 8.1 nM for human hGlyT1b and IC50 of 22-25 nM in Chinese hamster ovary cells.

CC(OC1=CC=C(C=C1C(=O)N2CCN(CC2)C3=NC=C(C=C3F)C(F)(F)F)[S](C)(=O)=O)C(F)(F)F

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