BK Beta2 Antibody (OASE00179)

Aviva Systems Biology

BK Beta2 Antibody (OASE00179)

23

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, Other Application

Research Use Only

Monoclonal

S53-32

1 mg/ml

Unconjugated

Kcnmb2

potassium large conductance calcium-activated channel, subfamily M, beta member 2

2700049B16Rik, 3110031N04Rik, calcium-activated potassium channel subunit beta-2, BK channel subunit beta-2, BKbeta2, calcium-activated potassium channel, subfamily M subunit beta-2, charybdotoxin receptor subunit beta-2, k(VCA)beta-2, maxi K channel subunit beta-2, slo-beta-2

Mouse

IgG1

BK channels contribute to electrical impulses, proper signal transmission of information and regulation of neurotransmitter release (1). A gain of function mutation in the pore-forming alpha subunit of the BK channel was linked to human neurological diseases. Findings suggest that the distribution of the beta subunits in the brain can modulate the BK channels to contribute to the pathophysiology of epilepsy and dyskinesia (2). This has major implications on other physiological processes in tissues other than the brain.

-20°C

12352203