BKM1644 [1070966-96-9]

MedChem Express

BKM1644 [1070966-96-9]

14

1070966-96-9

Research Use Only

C34H37Cl2F5N2O9P2

845.51

BKM1644, an acyl-tyrosine bisphosphonate amide derivative, exhibits potent anti-cancer activity. BKM1644 effectively inhibits the proliferation of metastatic, castration-resistant prostate cance (mCRPC) cells. BKM1644 sensitizes mCRPC cells to Docetaxel (HY-B0011) and retards the bone metastatic growth of prostate cance[1].

O=C(/C=C/C1=C(C(F)=C(C(F)=C1F)F)F)N[C@@H](C(NC(P(OCC)(OCC)=O)P(OCC)(OCC)=O)=O)CC2=CC=C(C=C2)OCC3=C(C=CC=C3Cl)Cl

12352200