BL-1249 [18200-13-0]
HY-108596
CAS Number18200-13-0
Product group Chemicals
Estimated Purity99.81
Molecular Weight291.35
Overview
- SupplierMedChem Express
- Product NameBL-1249 [18200-13-0]
- Delivery Days Customer5
- CAS Number18200-13-0
- CertificationResearch Use Only
- Estimated Purity99.81
- Molecular FormulaC17H17N5
- Molecular Weight291.35
- Scientific DescriptionBL-1249 is a nonsteroidal anti-inflammatory agent (NSAID) and a potassium channel activator. BL-1249 potently activates K2P2.1 (TREK-1) and K2P10.1 (TREK-2) with EC50 values of 5.5 microM and 8.0 microM, respectively. BL-1249 extracellular application activates all TREK subfamily members but has no effect on other K2P subfamilies. BL-1249 exhibits more selective for the bladder (EC50 of 1.26 microM) than vascular tissue (EC50 of 21.0 microM)[1][2].
- SMILESC1(NC2=C3CCCCC3=CC=C2)=CC=CC=C1C4=NN=NN4
- Storage Instruction-20°C
- UNSPSC12352200
![BL-1249 [18200-13-0]](https://www.targetmol.com/group3/M00/35/FE/CgoaEWayM-2ELtg-AAAAAJj0OlE574.png)