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BL-1249

HY-108596
MedChem Express
CAS Number18200-13-0
DownloadMSDS
Product group Chemicals
Estimated Purity99.81
Molecular Weight291.35
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Overview

  • Supplier
    MedChem Express
  • Product Name
    BL-1249 [18200-13-0]
  • Delivery Days Customer
    5
  • CAS Number
    18200-13-0
  • Certification
    Research Use Only
  • Estimated Purity
    99.81
  • Molecular Formula
    C17H17N5
  • Molecular Weight
    291.35
  • Scientific Description
    BL-1249 is a nonsteroidal anti-inflammatory agent (NSAID) and a potassium channel activator. BL-1249 potently activates K 2P 2.1 (TREK-1) and K 2P 10.1 (TREK-2) with EC 50 values of 5.5 microM and 8.0 microM, respectively. BL-1249 extracellular application activates all TREK subfamily members but has no effect on other K 2P subfamilies. BL-1249 exhibits more selective for the bladder ( EC 50 of 1.26 microM) than vascular tissue ( EC 50 of 21.0 microM) [1] [2] .
  • SMILES
    C1(NC2=C3CCCCC3=CC=C2)=CC=CC=C1C4=NN=NN4
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200