Bleomycin A2 [41432-97-7]

MedChem Express

Bleomycin A2 [41432-97-7]

10

41432-97-7

Research Use Only

C55H85N17O25S4

1512.62

Bleomycin A2, an antitumor antibiotic promoting DNA-degradation, is an aspartate/asparagine-beta-hydroxylase (AspH) inhibitor with an IC50 of 1.47 microM[1].

O=C(C1=NC([C@H](CC(N)=O)NC[C@H](N)C(N)=O)=NC(N)=C1C)N[C@H](C(N[C@H](C)[C@@H](O)[C@H](C)C(N[C@]([C@H](O)C)([H])C(NCCC2=NC(C3=NC(C(NCCC[S+](C)C)=O)=CS3)=CS2)=O)=O)=O)[C@H](C4=CN=CN4)O[C@H]5[C@H]([C@H]([C@@H]([C@@H](O5)CO)O)O)O[C@]6([H])[C@H]([C@H]([C@@H]([C@H](O6)CO)O)OC(N)=O)O.O=S([O-])(O)=O

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