Bleomycin A5 (hydrochloride) [55658-47-4]

MedChem Express

Bleomycin A5 (hydrochloride) [55658-47-4]

10

55658-47-4

Research Use Only

h302-h315-h317-h319-h334-h335-h361,p261-p264-p270-p271-p272-p280-p284-p302+p352-p304+p340-p305+p351+p338-p330-p362+p364-p403+p233-p405-p501

C57H90ClN19O21S2

1477.02

Bleomycin A5 (Pingyangmycin) hydrochloride is an anti-neoplastic glycoprotein antibiotic. Bleomycin A5 suppresses Drp1-mediated mitochondrial fission and induces apoptosis in human nasal polyp-derived fibroblasts. Bleomycin A5 hydrochloride has anticancer activities relying on its ability to produce RNA and DNA breaks, thus, leading to cell death[1][2][3][4]..

[H]Cl.O=C(C1=NC([C@H](CC(N)=O)NC[C@H](N)C(N)=O)=NC(N)=C1C)N[C@H](C(N[C@H](C)[C@@H](O)[C@H](C)C(N[C@]([C@H](O)C)([H])C(NCCC2=NC(C3=NC(C(NCCCNCCCCN)=O)=CS3)=CS2)=O)=O)=O)[C@H](C4=CN=CN4)O[C@H]5[C@H]([C@H]([C@H](O)[C@H](CO)O5)O)O[C@@]6([H])[C@H]([C@H]([C@H](O)[C@@H](CO)O6)OC(N)=O)O.[x]

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